Despite approximately 4,400 unresectable U.S. cases annually, high-stage basal cell carcinoma (BCC) is ill-defined.Develop a tumor (T) staging system for BCC predicting metastasis/death and compare its performance to AJCC 8th …
Comorbidity screening in Hidradenitis Suppurativa: evidence-based recommendations from the US and Canadian Hidradenitis Suppurativa Foundations.
Hidradenitis suppurativa (HS) is associated with comorbidities that contribute to poor health, impaired life quality, and mortality risk.To provide evidence-based screening recommendations for comorbidities linked to HS.Systematic reviews were performed …
Identification of clinically useful predictive genetic variants in pachyonychia congenita.
Pachyonychia congenita (PC) refers to a group of autosomal dominant disorders caused by mutations in five keratin genes (KRT16, KRT6A, KRT17, KRT6B, or KRT6C). Current disease classification is based on …
Super-high magnification dermoscopy can add information for the differential diagnosis between melanoma and atypical nevi.
Dermoscopy is the most used non-invasive imaging technique for the clinical diagnosis of melanoma (MM). Super-high magnification dermoscopy at 400x magnification (D400) has been recently developed and can reveal additional …
JAK inhibitors for atopic dermatitis: a promising treatment modality.
Atopic dermatitis (AD) is chronic, pruritic, inflammatory skin disease that affects a significant portion of the population in industrialized nations. For non-responders to conventional therapies, AD can significantly reduce sleep …
Validity and reliability of Patient-Reported Outcomes Measurement Information System Global Health scale in adults with atopic dermatitis.
Patient-Reported Outcomes Measurement Information System Global Health (PGH) was validated to assess health-related quality of life (HRQOL) in several diseases. Little is known about its measurement properties in adult atopic …
The efficacy and tolerability of tetracyclines and clindamycin plus rifampicin for the treatment of hidradenitis suppurativa; results of a prospective European cohort study.
Tetracyclines and clindamycin plus rifampicin combination therapy are both considered first-line therapy in current Hidradenitis Suppurativa (HS) guidelines. However, evidence for their efficacy is drawn from small studies, often without …
An Evidence-Based Guide to SARS-CoV-2 Vaccination of Patients on Immunotherapies in Dermatology.
Immune-mediated diseases and immunotherapeutics can negatively impact normal immune functioning and consequently vaccine safety and response. The COVID-19 pandemic has incited research aimed at developing a novel SARS-CoV-2 vaccine. As …
Bromhidrosis Treatment Modalities: A Literature Review.
Treatment options for Bromhidrosis include Botulinum toxin therapy, microwave-based therapy, laser therapy, and surgerical intervention. There have been limited studies comparing their efficacies.The purpose of this literature review is to …
Small molecule inhibitors and biologics in treating nail psoriasis: a systematic review and network meta-analysis.
Various systemic immunomodulating therapies have been investigated to treat nail psoriasis, but the efficacy remains unclear.To perform a systematic review and network meta-analysis (NMA) to evaluate the efficacy of small …